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Southern Illinois, a captivating region in the southern third of Illinois, offers a unique blend of natural beauty and cultural heritage, making it an ideal travel destination. Known for its picturesque landscapes, the area is bordered by the Mississippi and Ohio Rivers, providing stunning views and outdoor activities. Visitors can explore the Shawnee National Forest, a haven for hiking and nature enthusiasts.
For those seeking vibrant communities, the Metro East area, part of the St. Louis Metropolitan Area, and the Carbondale–Marion–Herrin region are bustling with life. Carbondale, home to Southern Illinois University, is a hub of education and culture.
Top attractions include the historic town of Belleville, the charming city of Alton, and the scenic Garden of the Gods. Whether you're interested in exploring quaint towns or enjoying the great outdoors, Southern Illinois offers diverse experiences for every traveler.
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Hotel in St. Louis · 84.04 mi from centre
8.8
554 reviews
Breakfast available
Located in St. Louis (Clayton), Le Méridien St. Louis Clayton is within a 5-minute drive of Washington University in St. Louis and Forest Park. This eco-certified hotel is 3 mi (4.9 km) from St. Louis Zoo and 6.8 mi (11 km) from St. Louis University.
Hotel in Ozarks, Festus · 84.08 mi from centre
7.8
746 reviews
Breakfast available
Located in Festus, La Quinta Inn & Suites by Wyndham Festus - St. Louis South is in a rural location, within a 5-minute drive of Jorkerst Memorial Park and Festus Public Library. This hotel is 3.5 mi (5.6 km) from Mississippi River and 1 mi (1.7 km) from Sunset Park.
Hotel in St. Louis · 84.10 mi from centre
8.8
2,699 reviews
Breakfast available
With a stay at Clayton Plaza Hotel & Extended Stay in St. Louis (Clayton), you'll be within a 5-minute drive of Washington University in St. Louis and Forest Park. This hotel is 8.2 mi (13.2 km) from St. Louis Union Station and 8.9 mi (14.4 km) from Busch Stadium.
Hotel in St. Louis County, Richmond Heights · 84.27 mi from centre
7.8
978 reviews
Breakfast available
With a stay at Homewood Suites by Hilton St Louis - Galleria in Richmond Heights (Clayton), you'll be a 3-minute drive from Forest Park and 5 minutes from Washington University in St. Louis. This hotel is 7.8 mi (12.5 km) from St. Louis Union Station and 8.5 mi (13.7 km) from Busch Stadium.
Hotel in Ozarks, Festus · 84.35 mi from centre
8.0
780 reviews
Breakfast available
With a stay at Comfort Inn Festus - St Louis South in Festus, you'll be within a 10-minute drive of Mississippi River and Jorkerst Memorial Park. This hotel is 0.8 mi (1.2 km) from Sunset Park and 1.2 mi (1.9 km) from Festus Public Library.
Hotel in St. Louis · 84.88 mi from centre
8.2
978 reviews
Breakfast available
With a stay at Hilton Garden Inn St. Louis Airport in St. Louis (Berkeley), you'll be within a 15-minute drive of Forest Park and Washington University in St. Louis. This hotel is 11.6 mi (18.6 km) from Gateway Arch and 11.7 mi (18.9 km) from St. Louis Union Station.
Hotel in Southern Illinois, Casey · 85.01 mi from centre
7.4
677 reviews
Breakfast available
With a stay at Days Inn & Suites by Wyndham Casey in Casey, you'll be within a 15-minute walk of World's Largest Rocking Chair and World's Largest Wind Chime. This hotel is 0.5 mi (0.8 km) from World's Largest Yardstick and 0.6 mi (1 km) from World's Largest Pencil.
Hotel in St. Louis · 86.00 mi from centre
9.0
156 reviews
Breakfast available
With a stay at Comfort Suites St. Louis - Sunset Hills in St. Louis, you'll be within a 15-minute drive of Forest Park and Washington University in St. Louis. This hotel is 10.2 mi (16.4 km) from St. Louis Zoo and 13.8 mi (22.1 km) from St. Louis Union Station.
Hotel in St. Louis, Saint Louis · 86.20 mi from centre
8.5
125 reviews
Breakfast available
Located in Saint Louis, 14 miles from St. Louis Gateway Arch, Holiday Inn St Louis SW - Route 66 by IHG provides accommodations with a seasonal outdoor swimming pool, free private parking, a fitness center and a restaurant. With free WiFi, this 3-star hotel offers a 24-hour front desk and an ATM. Guests can have a drink at the bar.
Guests at the hotel can enjoy a continental or an American breakfast.
A business center and vending machines with snacks and drinks are available on site at Holiday Inn St Louis SW - Route 66 by IHG.
Six Flags St. Louis is 17 miles from the accommodation, while Hollywood Casino St. Louis is 19 miles away. St. Louis Lambert International Airport is 16 miles from the property.
Hotel in St. Louis · 86.47 mi from centre
8.2
882 reviews
Breakfast available
With a stay at Renaissance St. Louis Airport Hotel in St. Louis (Berkeley), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles. This hotel is 7.3 mi (11.8 km) from Washington University in St. Louis and 8.8 mi (14.2 km) from St. Louis Zoo.
Hotel in St. Louis · 87.03 mi from centre
7.8
663 reviews
Breakfast available
With a stay at DoubleTree by Hilton St. Louis Airport in St. Louis (Woodson Terrace), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles. This family-friendly hotel is 7.5 mi (12 km) from Washington University in St. Louis and 9 mi (14.4 km) from St. Louis Zoo.
Hotel in St. Louis County, Florissant · 87.09 mi from centre
7.6
966 reviews
Breakfast available
When you stay at Quality Inn Florissant - St Louis in Florissant, you'll be near the airport, within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles. This hotel is 10.2 mi (16.4 km) from Washington University in St. Louis and 11.7 mi (18.8 km) from St. Louis Zoo.
Hotel in St. Louis · 87.20 mi from centre
7.4
949 reviews
Breakfast available
With a stay at Hilton St. Louis Airport in St. Louis (Woodson Terrace), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles. This hotel is 8.4 mi (13.5 km) from Washington University in St. Louis and 9.9 mi (15.9 km) from St. Louis Zoo.
Hotel in St. Louis · 87.22 mi from centre
Breakfast available
Located in St. Louis (Woodson Terrace), Hampton Inn By Hilton St Louis Airport is within a 15-minute drive of Hollywood Casino Amphitheatre and Westport Plaza. This hotel is 7.8 mi (12.6 km) from Washington University in St. Louis and 8.2 mi (13.3 km) from Forest Park.
Hotel in St. Louis County, Frontenac · 87.37 mi from centre
8.6
953 reviews
Breakfast available
When you stay at Hilton St. Louis Frontenac in Frontenac, you'll be in the business district, within a 10-minute drive of Forest Park and St. Louis Zoo. This hotel is 11.5 mi (18.4 km) from St. Louis Union Station and 12.2 mi (19.6 km) from Busch Stadium.
Hotel in St. Louis · 87.72 mi from centre
7.8
967 reviews
Breakfast available
With a stay at Marriott St. Louis Airport in St. Louis (Edmundson), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles. This hotel is 8.9 mi (14.3 km) from Washington University in St. Louis and 10.3 mi (16.6 km) from St. Louis Zoo.
Hotel in Southern Illinois, Mattoon · 87.81 mi from centre
8.2
697 reviews
Breakfast available
Located in Mattoon, Holiday Inn Express & Suites Mattoon by IHG is a 3-minute drive from Mattoon Peterson Park and 5 minutes from Mattoon City Hall. This hotel is 3.5 mi (5.6 km) from Sarah Bush Lincoln Hospital and 3.5 mi (5.6 km) from Kinzel Field.
Hotel in St. Louis County, St. Ann · 87.87 mi from centre
9.2
1,077 reviews
Breakfast available
When you stay at Wingate by Wyndham St. Louis Airport in St. Ann, you'll be near the airport, within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles. This hotel is 9 mi (14.5 km) from Washington University in St. Louis and 10.5 mi (16.9 km) from St. Louis Zoo.
Hotel in St. Louis County, Fenton · 88.01 mi from centre
9.0
30 reviews
Breakfast available
When you stay at Best Western Plus Fenton in Fenton, you'll be in the business district, within a 15-minute drive of Forest Park and Mississippi River. This hotel is 12.4 mi (19.9 km) from St. Louis Zoo and 12.4 mi (20 km) from Washington University in St. Louis.
Hotel in Southern Illinois, Mattoon · 88.14 mi from centre
7.4
667 reviews
Breakfast available
Located in Mattoon, Super 8 by Wyndham Mattoon is a 4-minute drive from Mattoon Peterson Park and 6 minutes from Mattoon City Hall. This hotel is 3.6 mi (5.9 km) from Kinzel Field and 3.7 mi (5.9 km) from Sarah Bush Lincoln Hospital.