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Southern Illinois, a captivating region in the southern third of Illinois, offers a unique blend of natural beauty and cultural heritage, making it an ideal travel destination. Known for its picturesque landscapes, the area is bordered by the Mississippi and Ohio Rivers, providing stunning views and outdoor activities. Visitors can explore the Shawnee National Forest, a haven for hiking and nature enthusiasts.
For those seeking vibrant communities, the Metro East area, part of the St. Louis Metropolitan Area, and the Carbondale–Marion–Herrin region are bustling with life. Carbondale, home to Southern Illinois University, is a hub of education and culture.
Top attractions include the historic town of Belleville, the charming city of Alton, and the scenic Garden of the Gods. Whether you're interested in exploring quaint towns or enjoying the great outdoors, Southern Illinois offers diverse experiences for every traveler.
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St. Louis Airport Hotel
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 138.74 km from centre
7.4
806 reviews
A stay at St. Louis Airport Hotel places you in the heart of St. Louis, within a 15-minute drive of Forest Park and Washington University in St. Louis. This hotel is 8.1 mi (13 km) from St. Louis Art Museum and 8.4 mi (13.6 km) from St. Louis Zoo.
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Holiday Inn St Louis SW - Route 66 by IHG
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 138.74 km from centre
9.0
210 reviews
Breakfast available
When you stay at Holiday Inn St Louis SW - Route 66 by IHG in St. Louis, you'll be in the business district, within a 15-minute drive of St. Louis Zoo and Forest Park. This hotel is 10.2 mi (16.4 km) from Washington University in St. Louis and 13.7 mi (22 km) from St. Louis Union Station.
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Travelodge by Wyndham St. Louis
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 138.76 km from centre
6.6
936 reviews
Breakfast available
With a stay at Travelodge by Wyndham St. Louis in St. Louis (Berkeley), you'll be within a 15-minute drive of St. Louis Zoo and Hollywood Casino Amphitheatre. This hotel is 11.4 mi (18.4 km) from St. Louis Union Station and 7.1 mi (11.5 km) from Washington University in St. Louis.
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Renaissance St. Louis Airport Hotel
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 139.16 km from centre
8.2
882 reviews
Breakfast available
With a stay at Renaissance St. Louis Airport Hotel in St. Louis (Berkeley), you'll be within a 15-minute drive of St. Louis Zoo and Hollywood Casino Amphitheatre. This hotel is 7.3 mi (11.8 km) from Washington University in St. Louis and 13.2 mi (21.2 km) from Enterprise Center.
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Holiday Inn Express & Suites St Louis Airport by IHG
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 139.67 km from centre
8.6
977 reviews
Breakfast available
With a stay at Holiday Inn Express & Suites St Louis Airport by IHG in St. Louis (Woodson Terrace), you'll be within a 15-minute drive of St. Louis Zoo and Hollywood Casino Amphitheatre. This hotel is 8 mi (12.9 km) from Washington University in St. Louis and 13.4 mi (21.5 km) from Enterprise Center.
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DoubleTree by Hilton St. Louis Airport
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 140.06 km from centre
7.8
663 reviews
Breakfast available
With a stay at DoubleTree by Hilton St. Louis Airport in St. Louis (Woodson Terrace), you'll be within a 15-minute drive of St. Louis Zoo and Hollywood Casino Amphitheatre. This family-friendly hotel is 7.5 mi (12 km) from Washington University in St. Louis and 13.7 mi (22.1 km) from Enterprise Center.
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Quality Inn Florissant - St Louis
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis County, Florissant · 140.16 km from centre
7.6
966 reviews
Breakfast available
When you stay at Quality Inn Florissant - St Louis in Florissant, you'll be near the airport, within a 15-minute drive of Hollywood Casino Amphitheatre and Westport Plaza. This hotel is 11.7 mi (18.8 km) from St. Louis Zoo and 10.2 mi (16.4 km) from Washington University in St. Louis.
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Quality Inn St. Louis Airport Hotel
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 140.16 km from centre
6.0
938 reviews
With a stay at Quality Inn St. Louis Airport Hotel in St. Louis (Woodson Terrace), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Westport Plaza. This hotel is 9.8 mi (15.7 km) from St. Louis Zoo and 8.3 mi (13.3 km) from Washington University in St. Louis.
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Hilton St. Louis Airport
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 140.33 km from centre
7.4
949 reviews
Breakfast available
With a stay at Hilton St. Louis Airport in St. Louis (Woodson Terrace), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Westport Plaza. This hotel is 9.9 mi (15.9 km) from St. Louis Zoo and 8.4 mi (13.5 km) from Washington University in St. Louis.
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Hilton St. Louis Frontenac
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis County, Frontenac · 140.61 km from centre
8.6
953 reviews
Breakfast available
When you stay at Hilton St. Louis Frontenac in Frontenac, you'll be in the business district, within a 10-minute drive of St. Louis Zoo and Forest Park. This hotel is 11.5 mi (18.4 km) from St. Louis Union Station and 11.7 mi (18.9 km) from Enterprise Center.
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Super 8 by Wyndham St. Louis Airport
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 140.75 km from centre
5.0
972 reviews
Breakfast available
With a stay at Super 8 by Wyndham St. Louis Airport in St. Louis (Breckenridge Hills), you'll be within a 15-minute drive of St. Louis Zoo and Hollywood Casino Amphitheatre. This hotel is 11.6 mi (18.6 km) from St. Louis Union Station and 12 mi (19.2 km) from Enterprise Center.
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Quality Inn Cairo I-57
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in Southern Illinois, Cairo · 140.87 km from centre
6.4
245 reviews
Breakfast available
With a stay at Quality Inn Cairo I-57 in Cairo, you'll be within a 15-minute drive of Mississippi River and Ohio River. This hotel is 7.9 mi (12.6 km) from Shawnee National Forest and 5.1 mi (8.1 km) from Fort Defiance State Park.
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Marriott St. Louis Airport
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis · 141.17 km from centre
7.8
967 reviews
Breakfast available
With a stay at Marriott St. Louis Airport in St. Louis (Edmundson), you'll be within a 15-minute drive of Hollywood Casino Amphitheatre and Westport Plaza. This hotel is 10.3 mi (16.6 km) from St. Louis Zoo and 8.9 mi (14.3 km) from Washington University in St. Louis.
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Holiday Inn Express & Suites Mattoon by IHG
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in Southern Illinois, Mattoon · 141.32 km from centre
8.2
697 reviews
Breakfast available
Located in Mattoon, Holiday Inn Express & Suites Mattoon by IHG is a 3-minute drive from Mattoon Peterson Park and 5 minutes from Mattoon City Hall. This hotel is 3.5 mi (5.6 km) from Sarah Bush Lincoln Hospital and 3.5 mi (5.6 km) from Kinzel Field.
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Wingate by Wyndham St. Louis Airport
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis County, St. Ann · 141.41 km from centre
9.2
1,077 reviews
Breakfast available
When you stay at Wingate by Wyndham St. Louis Airport in St. Ann, you'll be near the airport, within a 15-minute drive of Hollywood Casino Amphitheatre and Westport Plaza. This hotel is 10.5 mi (16.9 km) from St. Louis Zoo and 9 mi (14.5 km) from Washington University in St. Louis.
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Extended Stay America Suites - St Louis - Fenton
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis County, Fenton · 141.56 km from centre
5.6
172 reviews
With a stay at Extended Stay America Suites - St Louis - Fenton in Fenton, you'll be within a 15-minute drive of Forest Park and Meramec River. This hotel is 12.5 mi (20.1 km) from St. Louis Zoo and 12.5 mi (20.2 km) from Washington University in St. Louis.
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Best Western Plus Fenton
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis County, Fenton · 141.64 km from centre
9.0
30 reviews
Breakfast available
When you stay at Best Western Plus Fenton in Fenton, you'll be in the business district, within a 15-minute drive of Forest Park and Mississippi River. This hotel is 12.4 mi (19.9 km) from St. Louis Zoo and 12.4 mi (20 km) from Washington University in St. Louis.
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Comfort Suites Mattoon
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in Southern Illinois, Mattoon · 141.75 km from centre
8.6
687 reviews
Breakfast available
Located in Mattoon, Comfort Suites Mattoon is a 4-minute drive from Mattoon Peterson Park and 5 minutes from Mattoon City Hall. This hotel is 3.6 mi (5.8 km) from Kinzel Field and 3.6 mi (5.8 km) from Sarah Bush Lincoln Hospital.
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Super 8 by Wyndham Mattoon
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in Southern Illinois, Mattoon · 141.85 km from centre
7.4
667 reviews
Breakfast available
Located in Mattoon, Super 8 by Wyndham Mattoon is a 4-minute drive from Mattoon Peterson Park and 6 minutes from Mattoon City Hall. This hotel is 3.6 mi (5.9 km) from Kinzel Field and 3.7 mi (5.9 km) from Sarah Bush Lincoln Hospital.
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La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North
This star rating is provided to LateRooms by the property. It is usually determined by an official hotel rating organisation or another third party.
Hotel in St. Louis County, Hazelwood · 141.85 km from centre
6.2
921 reviews
Breakfast available
When you stay at La Quinta Inn by Wyndham St. Louis Hazelwood - Airport North in Hazelwood, you'll be in the business district, within a 15-minute drive of Hollywood Casino Amphitheatre and Ameristar Casino St. Charles. This hotel is 11.7 mi (18.8 km) from Washington University in St. Louis and 13.1 mi (21.1 km) from St. Louis Zoo.
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